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eye (1989) 3, 536–546; doi: 10.1038/eye.1989.85

The visual field in chronic simple glaucoma and ocular hypertension; its character, progress, relationship to the level of intraocular pressure and response to treatment

R P Crick1, R Vogel2, R B Newson3, M J Shipley3, H Blackmore1, A Palmer4 and C J Bulpitt4

  1. 1Eye Department, King's College Hospital, London
  2. 2M.S.D. Research Laboratories, West Point, P.A., U.S.A
  3. 3Department of Epidemiology, London School of Hygiene and Tropical Medicine, London
  4. 4Division of Geriatrics, Royal Postgraduate Medical School, London

Correspondence: R. P. Crick, Eye Department, King's College Hospital, Denmark Hill, London SE5 9RS, England

Supported by King's College Hospital Research Committee, International Glaucoma Association and M.S.D. Chibret.

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Nine hundred and twenty-nine patients with chronic simple glaucoma or ocular hypertension were followed for one to thirteen years using the King's College Hospital glaucoma data base.

The 30° visual field was divided into twelve clinical zones. The field sensitivity and its change as measured by the mean differential threshold both in these zones and overall was followed to determine the pattern and progress of field loss in eyes diagnosed initially as chronic simple glaucoma or ocular hypertension.

The findings were related to other similar analyses in which the mean differential threshold in chronic glaucoma was found to correlate significantly with the initial intraocular pressure and its progress with the mean follow-up intraocular pressure under treatment. Inferences were drawn regarding the nature of chronic simple glaucoma and ocular hypertension and their management.

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  1. Vogel R, Crick RP, Newson RB, Shipley M, Blackmore H, Bulpitt CJ: The association between intraocular pressure and loss of visual field in chronic simple glaucoma. Br J Ophthalmol (In Press).
  2. Crick RP: Prevention of blindness from glaucoma using the King's College Hospital computerised problem orientated medical record. Br J Ophthalmol 1975, 59: 236–48. | Article | PubMed | ISI |
  3. Aulhorn E: Comparative visual study in patients with primary open angle glaucoma and anterior ischaemic optic neuropathy. Doc Ophthalmol Proc 1980, 22: 3–13.
  4. Phelps CD, Hayreh SS, Montague PR: Visual fields in low tension glaucoma, primary open angle glaucoma and anterior ischaemic optic neuropathy. Doc Ophthalmol Proc 1983, 35: 113–24.
  5. Hollows FC, and Graham PA: The Ferndale glaucoma survey. In: HUNT L B Ed. Glaucoma, Edinburgh: Livingstone, 1966, 24–44.
  6. Bebie H: Compatibility of different Octopus models with respect to normal values. In: Proc. Third Octopus User's Meeting, Niagara Falls, N.Y. 1984, 41–43.
  7. Krakau CET: Discussion of paper by Leydhecker W. Is glaucoma therapy useless? In: Krieglstein GK and Leydhecker W Eds. Glaucoma update II. Springer-Verlag, Berlin. 1983, 100–101.
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  9. Bengtsson B: Aspects of the epidemiology of chronic glaucoma. Acta Ophthalmol (Suppl), Copenhagen 1981, 146: 1–48.
  10. Crick RP and Daubs JG: Epidemiological aids to clinical decision making in primary open angle glaucoma. Int. Ophthalmol. 1980, 3: 37–41. | Article | PubMed | ISI | ChemPort |
  11. Daubs JG and Crick RP: Blindness prevention through control of ocular hypertension: an epidemiological assessment. Int Ophthalmol 1980, 3: 43–9. | Article | PubMed | ISI |
  12. Quigley JA, Addicks EM, Green WR: Optic nerve damage in human glaucoma. Arch Ophthalmol 1982, 100: 135–46. | PubMed | ISI | ChemPort |
  13. Wilson R, Walker AM, Dueker DK, Crick RP: Risk factors for progressive glaucomatous visual field loss: A computer based analysis. Arch Ophthalmol 1982, 100: 737–4l. | PubMed | ISI |
  14. Bodis-Wallner I, Atkin A, Nitzberg S, Mylin L: Psychophysical investigation of abnormalities in contrast sensitivity in glaucoma. In: Leydhecker W and Krieglstein G (Eds) Ocular Hypertension Heidelberg, Kaden Verlag, 1983, 69–77.
  15. Daubs J, Crick R, Reynolds P: The Arden gratings test as a risk indicator for field loss among glaucoma patients. Glaucoma 1984, 6: 248–54.
  16. Alvarez SL and Mills KB: Spectral and flicker sensitivity in ocular hypertension and glaucoma. Res Clin Forums 1985, 7: 83–94.

Источник: http://www.nature.com/eye/journal/v3/n5/abs/eye198...

Глаукома msd

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